TumorManagerTM is a fully integrated program that allows scientists to manage every aspect of their subcutaneous xenograft tumor studies. Using an intuitive user friendly interface the program allows complete control of every step including:
Data obtained from calipers often is manually recorded on paper or entered into an Excel spreadsheet in the laboratory. Both these processes are prone to errors. A few of these problems are summarized below:
Extensive involvement of human operators can cause transcription errors, either when recording the data in the laboratory during the measurement phase, or when transferring data to a spreadsheet. Protocols often change from one study to another, e.g. the number of animals, or the number of groups. Modifying spreadsheet templates to adapt to these new parameters can also cause additional errors.
Paper or Excel-based results are generally static; therefore, real time information such as Tumor Doubling Time (TDT), Log Cell Kill (LCK), T/C etc is not available to the scientist. Using TumorManagerTM these important parameters are calculated and plotted after every measurement is made. Parameters such as TDT can be very useful to a researcher to monitor the progress of a study when they are available instantaneously.
Spreadsheet programs typically have very limited statistical analysis capabilities. They do not provide ANOVA based multiple comparison analyses (e.g. Dunnett, Duncan etc.), or Kaplan Maier survival analysis. Data from these spreadsheets needs to be transferred to a commercial statistical analysis program for further analysis adding to the complexity and time required. The turnaround time can be even longer if the data must sent to a biostatistician for further analysis.
TumorManagerTM is a program designed to eliminate all of the above mentioned problems. TumorManagerTM stores all data in a standard MS SQL Server database. Data inquiry and storage are validated. When each measurement is taken all information related to that data including the identity of experimenter, date and time of the measurement and the device used is recorded. TumorManagerTM protocols are defined by the study director ensuring full user compliance even the nomenclature to be used.